Study Reveals 'Most Effective
    Diet'
    Scientists at Aberdeen’s Rowett Research Institute have shown that a
    high protein, low carbohydrate diet is most effective at reducing hunger
    and promoting weight loss, at least in the short term.

    Healthy, obese men were given two different diets during their stay in the
    Rowett’s specialised Human Nutrition Unit.  Both diets had a high protein
    content (30% of total energy value of the diet) but they differed in the
    amount of carbohydrate:  One diet was low in carbohydrate (4%) and the
    other contained a moderate amount of carbohydrate (35% total energy
    value).

    “Our volunteers found both diets to be equally palatable, but they felt less
    hungry on the high-protein low-carbohydrate diet compared with the diet
    which contained high-protein but moderate amounts of carbohydrate,”
    said Dr Alex Johnstone, the Rowett’s weight-loss expert who led the study.

    “Weight loss during the two four week study periods was greater on the
    high-protein low-carbohydrate diet, averaging 6.3 kg per person,
    compared with 4.3 kg on the moderate carbohydrate diet,” said Dr
    Johnstone.

    An important part of this study was to unravel the physiological
    mechanisms behind this type of diet.  It is known that when people eat
    low carbohydrate diets, within a relatively short time their body has to
    switch from using glucose as a fuel to using something different called
    ketone bodies. Ketone bodies are appetite-suppressing and they may
    have an effect on the appetite centres in the brain. It’s also well known
    that protein itself is very good at making people feel full-up.

    “In this study, we showed that on the high-protein low-carbohydrate diet
    the volunteers  became ketogenic within 1-2 days of starting this diet and
    so it may be that high-protein, low-carbohydrate diets are particularly
    effective because of the combined effect of the protein and the ketone
    bodies,” said Dr Johnstone.

    “We showed that the volunteers on the ketogenic diet reduced their
    energy intake without increasing their hunger and this was a very
    important factor in their ability to stick to the diet.”

    However, Dr Johnstone sounds a note of caution about her findings.

    “A paper published last year from the same study showed that low
    carbohydrate diets may have consequences for the health of the gut by
    dramatically reducing the numbers of particular types of bacteria.  So we
    will be looking in more detail at the complex way in which we respond to
    changes in our diet before we can say whether low-carbohydrate
    ketogenic diets are a suitable tool for everyone who wants to lose weight.”

    When the phase of the study which involved the volunteers finished in
    October 2004, it attracted considerable interest because of its celebrity
    volunteer, Cameron Stout, who lost just over 12 kg during his nine week
    stay at the Rowett Institute.  At the time, Cameron mentioned his surprise
    at not feeling hungry during the study and said he had adjusted to eating
    smaller portions.  How does he feel now, three years later?

    “I had a great experience with the nutrition study at the Rowett.  The food
    was excellent and the staff looked after us very well.  Because I have such
    an irregular lifestyle I don’t find it easy to stick rigidly to all that I learnt
    while I was at the Institute, but I try to make an effort most of the time.  For
    me it was mainly about breaking bad habits – and I guess we all have
    food vices we need to deal with!”  said Cameron.

    The study appears in the American Journal of Clinical Nutrition.
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